D(-)-ribose structural formula

D(-)-ribose structural formula

Structural formula

Business number 0141
Molecular formula C5H10O5
Molecular weight 150.13

D-crisp ribose,

Heterosexual gummy candy,


FEMA 3793,





Biochemical reagents, sweeteners and condiments

Numbering system

CAS number:50-69-1

MDL number:MFCD00135453

EINECS number:200-059-4

RTECS number:VJ2275000

BRN number:1723081

PubChem number:24901881

Physical property data

1. Properties: white crystal or crystalline powder, slightly aromatic. 2. Density (g/mL, 25/4℃): Undetermined

3. Relative vapor density (g/mL, air=1): Undetermined

4. Melting point (ºC): 955. Crystal Phase standard combustion heat (enthalpy) (kJ·mol-1): -2345.66. Crystal phase standard claim heat (enthalpy) (kJ·mol-1): – 1051.17. Refractive index: -21 ° (C=1, H2O)

8. Flash point (ºC): Undetermined

9. Specific rotation (º): -20.8 º (c= 4, H2O)

10. Autoignition point or ignition temperature (ºC): Undetermined

11. Vapor pressure (kPa, 25 ºC): Undetermined

12. Saturated vapor pressure (kPa, 60 ºC): Undetermined

13. Heat of combustion (KJ/mol): Undetermined

14. Critical temperature (ºC): Undetermined

15. Critical pressure (KPa): Undetermined

16. Log value of oil-water (octanol/water) partition coefficient: Undetermined

17. Explosion upper limit (%, V/V): Undetermined

18. Explosion lower limit (%, V/V): Undetermined

19. Solubility: can be dissolved in Water and methanol easily absorb moisture, tend to be supersaturated in water, and are slightly soluble in ethanol.

Toxicological data

1. Reproductive toxicity: Intrauterine TDLo of female mice: 5045ug/kg, conception occurs two days later; 2. Mutagenicity: DNA inhibition detection system: human lymphocytes: 50mmol/L; mutation testing system – not other specifiedTEST systems: Human lymphocytes: 30mmol/L

Ecological data


Molecular structure data

1. Molar refractive index: 31.05

2. Molar volume (cm3/mol): 89.2

3. Isotonic specific volume (90.2K): 266.0

4. Surface tension (dyne/cm): 78.7

5. Polarizability ( 10-24cm3): 12.31

Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): None

2. Number of hydrogen bond donors: 4

3. Number of hydrogen bond acceptors: 5

4. Number of rotatable chemical bonds: 4

5. Number of tautomers: 5

6. Topological molecule polar surface area 98

7. Number of heavy atoms: 10

8. Surface charge: 0

9. Complexity: 104

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 3

12. Uncertain number of atomic stereocenters: 0

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Properties and stability


Storage method

Store in a cool place after airtight packaging.

Synthesis method

Use D-glucose as raw material, add bacteria or Bacillus subtilis for fermentation, and separate and refine the fermentation products.

Preservation of bacterial strains → Activated slope → Seed tank culture → Fermentation → Fermentation broth →

Flocculation → Supernatant → Cationic resin exchange → Activated carbon decolorization → Concentration



D-ribose plays an important role in the pharmaceutical industry, food industry, agriculture and life science research. In the pharmaceutical industry, it is a very useful biochemical reagent, pharmaceutical and pharmaceutical synthesis intermediate. In the food industry, it can be used as a sweetener and condiment, as well as a crop growth promoter and feed additive.