histamine phosphate

Histamine phosphate structural formula

Histamine phosphate structural formula

Structural formula

Physical competition number 0155
Molecular formula C5H9N3·2H3PO4
Molecular weight 307.13

Histamine diphosphate,

histamine phosphate,

Histamine diphosphate,

Histamine diphosphate

Numbering system

CAS number:51-74-1

MDL number:MFCD00150816

EINECS number:24877940

RTECS number:NI5425000

BRN number:3744619

PubChem ID:None

Physical property data

1. Character: Colorless prismatic crystal Or white crystalline powder. Odorless.

2. Density (g/mL,25/4): Undetermined

3. Relative vapor density (g/mL,AIR=1): Undetermined

4. Melting point (ºC): 140

5. Boiling point (ºC,Normal pressure): Undetermined

6. Boiling point (ºC,5.2kPa): Undetermined

7. Refractive index : Undetermined

8. Flashpoint (ºC): Undetermined

9. Specific optical rotation (º):Undetermined

10. Autoignition point or ignition temperature (ºC): Undetermined

11. Vapor pressure (kPa,25ºC): Undetermined

12. Saturation vapor pressure (kPa,60ºC): Undetermined

13. Heat of combustion (KJ/mol): Undetermined

14. Critical temperature (ºC): Undetermined

15. Critical pressure (KPa): Undetermined

16. Oil and water (octanol/Logarithmic value of partition coefficient (water): undetermined

17. Explosion limit (%,V/V): Undetermined

18. Lower explosion limit (%,V/V): Undetermined

19. Solubility: Soluble in4Part of water, slightly soluble in ethanol, almost insoluble in ether. Aqueous solutions are acidic to litmus.

Toxicological data

1, acute toxicity: rat abdominal cavity LD50: 1781 mg/kg; rat intravenous LDLo: 900 mg/kg; mouse intravenous Oral LD50: 807mg/kg; mouse abdominal cavity LD50: 913 mg/kg;
Mouse vein LD50: 333mg/kg; Rabbit vein LD50: 2763ug/kg; rabbit parenteral LDLo: 1 mg /kg; Guinea pig vein LD50: 608ug/kg;
Guinea pig parenteral LD50: 746ug/kg;
2, Reproductive toxicity: parenteral in female miceTDLo: 62500ug/kg, 8 days after conception

Ecological data


Molecular structure data


Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP):

2. Number of hydrogen bond donors: 8

3. Number of hydrogen bond acceptors: 10

4. Number of rotatable chemical bonds: 2

5. Number of tautomers: 2

6. Topological molecular polar surface area (TPSA): 210

7. Number of heavy atoms: 18

8. Surface charge: 0

9. Complexity: 115

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 0

12. The number of uncertain atomic stereocenters: 0

13. Determine the number of stereocenters of chemical bonds: 0

14. Uncertain number of chemical bond stereocenters: 0

15. Number of covalent bond units: 3

Properties and stability

Hygroscopic. Stable in air, but deteriorated by light. Aqueous solutions are acidic to litmus.

Storage method

Should be sealed Store in a dry and dark place.

Synthesis method



Biochemical studies, determination of substrates for histaminase.