Tetramethylammonium chloride

Tetramethylammonium chloride structural formula

Structural formula

Business number 01JS
Molecular formula C4H12ClN
Molecular weight 109.60

Tetramethylammonium chloride,

Tetramethylammonium chloride,

Tetramethylammonium chloride,


N,N,N-Trimethylmethanaminium chloride,

Tetramine chloride,


Genetic engineering research reagents

Numbering system

CAS number:75-57-0

MDL number:MFCD00011628

EINECS number:200-880-8

RTECS number:BS7700000

BRN number:2496575

PubChem number:24888936

Physical property data

1. Properties: This product is white crystal. It is volatile and easy to deliquesce.

2. Density (g/mL, 25/4℃): 1.169

3. Relative vapor density (g/mL, air=1): Uncertain

4. Melting point (ºC): 420 °C.

5. Boiling point (ºC, normal pressure): 230

6. Boiling point (ºC, 5.2kPa): Uncertain

7. Refractive index: No Confirm

8. Flash point (ºC): Uncertain

9. Specific rotation (º): Uncertain

10. Autoignition point or ignition Temperature (ºC): Uncertain

11. Vapor pressure (kPa, 25ºC): Uncertain

12. Saturated vapor pressure (kPa, 60ºC): Uncertain

13. Heat of combustion (KJ/mol): Uncertain

14. Critical temperature (ºC): Uncertain

15. Critical pressure (KPa): Uncertain

16. The logarithmic value of the oil-water (octanol/water) partition coefficient: Uncertain

17. The upper limit of explosion (%, V/V): Uncertain

18. Lower explosion limit (%, V/V): Uncertain

19. Solubility: Easily soluble in methanol, soluble in water and hot ethanol, insoluble in ether and chloroform.

Toxicological data

1. Acute toxicity

Mouse caliber LC50: 125mg/kg

Mouse abdominal LC50: 25mg/kg

Mouse subcutaneous LC50: 40mg /kg

Mouse LCLO: 20 mg/kg

Rabbit subcutaneous LDLO: 6 mg/kg

Pig LDLO: 20 mg/kg

Frog subcutaneous LD50: 2mg/kg

Ecological data


Molecular structure data


Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): None

2. Number of hydrogen bond donors: 0

3. Number of hydrogen bond acceptorsAmount: 1

4. Number of rotatable chemical bonds: 0

5. Number of tautomers: None

6. Topological molecule polar surface area 0

7. Number of heavy atoms: 6

8. Surface charge: 0

9. Complexity: 19.1

10. Isotopes Number of atoms: 0

11. Determine the number of atomic stereocenters: 0

12. Uncertain number of atomic stereocenters: 0

13. Determine chemical bonds Number of stereocenters: 0

14. Number of stereocenters of uncertain chemical bonds: 0

15. Number of covalent bond units: 2

Properties and stability

1. Heated to 230ºC, it decomposes into trimethylamine and methyl chloride.

Storage method

This product should be sealed and stored in a cool, dry place away from light.

Synthesis method

1. Formic acid, formaldehyde and ammonia react to form trimethylamine formate:

Trimethylaminoformate and sodium hydroxide The trimethylamine released by the reaction reacts with methyl chloride to generate tetramethylammonium chloride:


1. Polarographic analysis reagents, chemical analysis reagents. Used in electronic industry, etc.